Acne Medications
Certain medications are used to address several problems that are possible 
causes of 
acne, such as:
- Abnormal clumping of cells in the follicles
- Increased oil production
- Bacteria
- Inflammation. 
Depending on the extent of the person's acne, the doctor will recommend one 
of several over-the-counter (OTC) medications or prescription medicines. 
Prescription medications for acne may be topical (applied to the skin) or 
systemic (taken by mouth). The doctor may suggest using multiple topical 
medications or combining oral and topical medications.
Doctors usually recommend an OTC or prescription topical acne medication 
for people with mild signs of acne. Topical medications are applied directly to 
the acne lesions or to the entire area of affected skin.
Common topical OTC medications for acne include:
- Benzoyl peroxide
- Resorcinol
- Salicylic acid
- Sulfur. 
Each of these drugs works a little differently. Benzoyl peroxide is best at 
killing Propionibacterium acnes bacteria and may also reduce oil 
production. Resorcinol, salicylic acid, and sulfur help break down blackheads 
and whiteheads (see Types of Acne). Salicylic acid also 
helps cut down the shedding of cells lining the follicles of the oil glands. 
Topical OTC acne medicines are available in many forms, such as:
- Gels
- Lotions
- Creams
- Soaps
- Pads. 
In some patients, OTC medications for acne may cause side effects such as 
skin irritation, burning, or redness. Some people find that the side effects 
lessen or go away with continued use of the medicine. Severe or prolonged side 
effects should be reported to the doctor.
OTC topical medications are somewhat effective in treating acne when used 
regularly. Patients must keep in mind that it can take eight weeks or more 
before they notice their skin looks and feels better.
Patients with moderate to severe inflammatory acne may be treated with 
prescription topical or oral medications, alone or in combination.
Several types of prescription topical medications are used for acne 
treatment, including:
- Antibiotics
- Benzoyl peroxide
- Tretinoin
- Adapalene
- Azelaic acid. 
Antibiotics and azelaic acid help stop or slow the growth of bacteria and 
reduce inflammation. Tretinoin, a type of drug called a retinoid that contains 
an altered form of vitamin A, is an 
effective topical acne medication for stopping the development of new comedones 
(basic acne lesions). It works by unplugging existing comedones, thereby 
allowing other topical acne medications, such as antibiotics, to enter the 
follicles. The doctor may also prescribe newer retinoids or retinoid-like drugs, 
such as tazarotene 
or adapalene, which help decrease comedo formation.
Like OTC topical medications, prescription topical medications for acne 
come as creams, lotions, solutions, or gels. The doctor will consider the 
patient's skin type when prescribing a product. Creams and lotions provide 
moisture and tend to be good for people with sensitive skin. Gels and solutions 
are generally alcohol based and tend to dry the skin. Therefore, patients with 
very oily skin or those who live in hot, humid climates may prefer them. The 
doctor will tell the patient how to apply the medication and how often to use 
it.
Some people develop side effects from using prescription topical acne 
medications. Initially, the skin may look worse before improving. Common side 
effects include:
- Stinging
- Burning
- Redness
- Peeling
- Scaling
- Discoloration of the skin. 
With some medications for acne, like retinoids, these side effects usually 
decrease or go away after the medicine is used for a period of time. Patients 
should report prolonged or severe side effects to their doctor. Between four and 
eight weeks will most likely pass before patients see their skin improve.
 
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